BDBM50135165 (+)-gallocatechin::(2R,3S)-2-(3,4,5-Trihydroxy-phenyl)-chroman-3,5,7-triol::CHEMBL125743

SMILES O[C@H]1Cc2c(O)cc(O)cc2O[C@@H]1c1cc(O)c(O)c(O)c1

InChI Key InChIKey=XMOCLSLCDHWDHP-SWLSCSKDSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50135165   

LigandPNGBDBM50135165((+)-gallocatechin | (2R,3S)-2-(3,4,5-Trihydroxy-ph...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of NLWAAQRYGRELRRMSD-K(FITC)-FVD from Bcl-2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article

TargetMitogen-activated protein kinase 10(Human)
Eberhard Karls University of Tuebingen

LigandPNGBDBM50135165((+)-gallocatechin | (2R,3S)-2-(3,4,5-Trihydroxy-ph...)
Affinity DataIC50:  5.30E+3nMT: 37°CAssay Description:The p38alpha reaction was carried out by using kinase (12ng per well), ATP (100uM) and incubated for 60 min at 37 C. For the JNK3 assay, kinase (10n...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-synuclein(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50135165((+)-gallocatechin | (2R,3S)-2-(3,4,5-Trihydroxy-ph...)
Affinity DataIC50:  8.90E+3nMAssay Description:Inhibition of human alpha-synuclein filament formation expressed in Escherichia coli BL21(DE3) cells incubated for 72 hrs by thioflavin S based fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin G/H synthase 1(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50135165((+)-gallocatechin | (2R,3S)-2-(3,4,5-Trihydroxy-ph...)
Affinity DataIC50:  9.50E+4nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 14(Human)
Eberhard Karls University of Tuebingen

LigandPNGBDBM50135165((+)-gallocatechin | (2R,3S)-2-(3,4,5-Trihydroxy-ph...)
Affinity DataIC50:  3.53E+3nMT: 37°CAssay Description:The p38alpha reaction was carried out by using kinase (12ng per well), ATP (100uM) and incubated for 60 min at 37 C. For the JNK3 assay, kinase (10n...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Kyungpook National University

Curated by ChEMBL
LigandPNGBDBM50135165((+)-gallocatechin | (2R,3S)-2-(3,4,5-Trihydroxy-ph...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human Beta-secretase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed