BDBM50135298 1-(2,6-Dichloro-phenyl)-6-(2,6-dimethyl-phenylsulfanyl)-3,4-dihydro-1H-pyrido[3,2-d]pyrimidin-2-one::CHEMBL129174

SMILES Cc1cccc(C)c1Sc1ccc2N(C(=O)NCc2n1)c1c(Cl)cccc1Cl

InChI Key InChIKey=VQKZUBKJYLJTPX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50135298   

TargetMitogen-activated protein kinase 14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50135298(1-(2,6-Dichloro-phenyl)-6-(2,6-dimethyl-phenylsulf...)
Affinity DataIC50: 260nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50135298(1-(2,6-Dichloro-phenyl)-6-(2,6-dimethyl-phenylsulf...)
Affinity DataIC50: 980nMAssay Description:Inhibitory activity against mitogen-activated protein kinase p38 betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed