BDBM50135318 1-(2,6-Dichloro-phenyl)-6-o-tolylsulfanyl-3,4-dihydro-1H-pyrido[3,2-d]pyrimidin-2-one::1-(2,6-dichlorophenyl)-6-(o-tolylthio)-3,4-dihydropyrido[3,2-d]pyrimidin-2(1H)-one::CHEMBL443285

SMILES Cc1ccccc1Sc1ccc2N(C(=O)NCc2n1)c1c(Cl)cccc1Cl

InChI Key InChIKey=UZEBTLKJBIERRJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50135318   

TargetMitogen-activated protein kinase 14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50135318(1-(2,6-dichlorophenyl)-6-(o-tolylthio)-3,4-dihydro...)
Affinity DataIC50: 110nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50135318(1-(2,6-dichlorophenyl)-6-(o-tolylthio)-3,4-dihydro...)
Affinity DataIC50: 800nMAssay Description:Inhibitory activity against mitogen-activated protein kinase p38 betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed