BDBM50135322 6-(2-Bromo-phenylsulfanyl)-1-(2,6-dichloro-phenyl)-3,4-dihydro-1H-pyrido[3,2-d]pyrimidin-2-one::CHEMBL131194

SMILES Clc1cccc(Cl)c1N1C(=O)NCc2nc(Sc3ccccc3Br)ccc12

InChI Key InChIKey=DZNGNORQVUAHBQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50135322   

TargetMitogen-activated protein kinase 14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50135322(6-(2-Bromo-phenylsulfanyl)-1-(2,6-dichloro-phenyl)...)
Affinity DataIC50: 120nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50135322(6-(2-Bromo-phenylsulfanyl)-1-(2,6-dichloro-phenyl)...)
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibitory activity against mitogen-activated protein kinase p38 betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed