BDBM50135455 (2E,4E,6Z)-7-(5-Isopropyl-3-pentafluoroethyl-2-propoxy-phenyl)-3-methyl-octa-2,4,6-trienoic acid::CHEMBL131122
SMILES CCCOc1c(cc(cc1C(F)(F)C(F)(F)F)C(C)C)C(\C)=C/C=C/C(/C)=C/C(O)=O
InChI Key InChIKey=QZNALCLAYUARIR-ZHOIUTETSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50135455
Affinity DataKi: 9.90nMAssay Description:Displacement of [3H]-9-cis-RA from RXR beta receptor in CV-1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Binding affinity against RXR gamma receptor using [3H]-9-cis-RA as radioligand in CV-1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 86nMAssay Description:In vitro agonist efficacy against PPAR gamma along with 100 nM BRL49653More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-ATRA from RAR gamma receptor expressed in CV-1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity against RAR beta receptor using [3H]-ATRA as radioligand in CV-1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity against RAR alpha receptor using [3H]-ATRA as radioligand in CV-1 cellsMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Human)
Ligand Pharmaceuticals
Curated by ChEMBL
Ligand Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 15nMAssay Description:In vitro anatagonist activity against RXR alpha in CV-1 cellsMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Human)
Ligand Pharmaceuticals
Curated by ChEMBL
Ligand Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 29nMAssay Description:In vitro agonist efficacy against PPAR gamma along with 100 nM BRL49653More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:In vitro anatagonist activity against RXR alpha in CV-1 cellsMore data for this Ligand-Target Pair