BDBM50135673 3-Diethylaminomethyl-pyrimido[5,4-e][1,2,4]triazine-5,7-diamine::CHEMBL95255

SMILES CCN(CC)Cc1nnc2nc(N)nc(N)c2n1

InChI Key InChIKey=YQHZTGWSLGCDMD-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50135673   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135673(3-Diethylaminomethyl-pyrimido[5,4-e][1,2,4]triazin...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B in 2 mM DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135673(3-Diethylaminomethyl-pyrimido[5,4-e][1,2,4]triazin...)
Affinity DataIC50:  2.80E+4nMAssay Description:In vitro inhibitory concentration required against Leukocyte antigen related receptor phosphatase (LAR) in the presence of 300 nM DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135673(3-Diethylaminomethyl-pyrimido[5,4-e][1,2,4]triazin...)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B in 300 nM DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135673(3-Diethylaminomethyl-pyrimido[5,4-e][1,2,4]triazin...)
Affinity DataIC50:  1.40E+4nMAssay Description:In vitro inhibitory concentration required against Tyrosine phosphatase SHP-2 in the presence of 300 nM DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135673(3-Diethylaminomethyl-pyrimido[5,4-e][1,2,4]triazin...)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B in 300 nM DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135673(3-Diethylaminomethyl-pyrimido[5,4-e][1,2,4]triazin...)
Affinity DataIC50:  2.80E+4nMAssay Description:In vitro inhibitory concentration required against Protein-tyrosine phosphatase alpha in the presence of 300 nM DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed