BDBM50135824 (Bis-phosphono-methyl)-cyclopentyl-ammonium::(Cyclopentylamino-phosphono-methyl)-phosphonic acid::(cyclopentylamino)methylenediphosphonic acid::CHEMBL58830::cyclopentylaminomethylene-1,1-bisphosphonate

SMILES OP(O)(O)C(=NC1CCCC1)P(O)(O)=O

InChI Key InChIKey=NBTSAPCYHIZNTR-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50135824   

TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135824((cyclopentylamino)methylenediphosphonic acid | cyc...)
Affinity DataKi:  52nMAssay Description:Binding affinity towards farnesyl Pyrophosphate Synthase using [14C]- isopentenyl pyrophosphate as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135824((cyclopentylamino)methylenediphosphonic acid | cyc...)
Affinity DataIC50: 537nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase expressed as #NAME (M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135824((cyclopentylamino)methylenediphosphonic acid | cyc...)
Affinity DataIC50: 540nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyprenyl synthetase family protein(Leishmania donovani)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135824((cyclopentylamino)methylenediphosphonic acid | cyc...)
Affinity DataIC50: 540nMAssay Description:Inhibitory activity against Leishmania major Farnesyl diphosphate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed