BDBM50135942 2-[2-(2-Amino-ethyl)-phenyl]-5-trifluoromethyl-2H-pyrazole-3-carboxylic acid (3-fluoro-2'-methanesulfonyl-biphenyl-4-yl)-amide::CHEMBL423759

SMILES CS(=O)(=O)c1ccccc1-c1ccc(NC(=O)c2cc(nn2-c2ccccc2CCN)C(F)(F)F)c(F)c1

InChI Key InChIKey=SMYLEWDHZPISRT-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50135942   

TargetCoagulation factor X(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50135942(2-[2-(2-Amino-ethyl)-phenyl]-5-trifluoromethyl-2H-...)
Affinity DataKi:  110nMAssay Description:Tested in vitro for inhibition of human Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50135942(2-[2-(2-Amino-ethyl)-phenyl]-5-trifluoromethyl-2H-...)
Affinity DataKi: >2.50E+3nMAssay Description:Tested in vitro for inhibition of human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50135942(2-[2-(2-Amino-ethyl)-phenyl]-5-trifluoromethyl-2H-...)
Affinity DataKi: >2.10E+4nMAssay Description:In vitro for inhibition of human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed