BDBM50136116 7-[2-benzylamino(imino)methylaminoethyl]-22-cyclopropylmethyl-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15,17,19(25)-heptaene-2,16-diol

SMILES N=C(NCCc1ccc2[nH]c3c(c2c1)C[C@@]1(O)C2Cc4ccc(O)c5c4[C@@]1(CCN2CC1CC1)[C@H]3O5)NCc1ccccc1

InChI Key InChIKey=ZJXDXDBINNENEV-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50136116   

TargetKappa-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136116BDBM50136116(7-[2-benzylamino(imino)methylaminoethyl]-22-cyclop...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity against cloned human Opioid receptor kappa 1 transfected into chinese hamster ovary cells using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136116BDBM50136116(7-[2-benzylamino(imino)methylaminoethyl]-22-cyclop...)
Affinity DataKi:  3.5nMAssay Description:Binding affinity against cloned human Opioid receptor mu 1 transfected into chinese hamster ovary cells using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136116BDBM50136116(7-[2-benzylamino(imino)methylaminoethyl]-22-cyclop...)
Affinity DataKi:  7.20nMAssay Description:Binding affinity against cloned human Opioid receptor delta 1 transfected into chinese hamster ovary cells using [3H]Cl-DPDPE as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed