BDBM50136274 (3R,4S)-1-(Furan-2-carbonyl)-piperidine-3,4-dicarboxylic acid 3-hydroxyamide 4-{[4-(quinolin-4-yloxymethyl)-phenyl]-amide}::CHEMBL132928

SMILES ONC(=O)[C@H]1CN(CC[C@@H]1C(=O)Nc1ccc(COc2ccnc3ccccc23)cc1)C(=O)c1ccco1

InChI Key InChIKey=UIQCNEYBEDSLMK-UNMCSNQZSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50136274   

TargetMatrix metalloproteinase-9(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136274((3R,4S)-1-(Furan-2-carbonyl)-piperidine-3,4-dicarb...)
Affinity DataKi: >2.13E+3nMAssay Description:Inhibitory activity against matrix metalloproteinase-9 (MMP-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target72 kDa type IV collagenase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136274((3R,4S)-1-(Furan-2-carbonyl)-piperidine-3,4-dicarb...)
Affinity DataKi: >3.33E+3nMAssay Description:Inhibitory activity against matrix metalloproteinase-2 (MMP-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInterstitial collagenase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136274((3R,4S)-1-(Furan-2-carbonyl)-piperidine-3,4-dicarb...)
Affinity DataKi: >4.95E+3nMAssay Description:Inhibitory activity of the compound against matrix metalloproteinase-1(MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136274((3R,4S)-1-(Furan-2-carbonyl)-piperidine-3,4-dicarb...)
Affinity DataIC50:  0.800nMAssay Description:In vitro binding affinity against porcine TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed