BDBM50136430 5-Chloro-1H-indole-2-carboxylic acid ((R)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl)-amide::CHEMBL134797

SMILES O=C(N[C@@H]1CCc2ccccc2NC1=O)c1cc2cc(Cl)ccc2[nH]1

InChI Key InChIKey=VKSJJHHQYWOARV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50136430   

TargetGlycogen phosphorylase, muscle form(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136430BDBM50136430(5-Chloro-1H-indole-2-carboxylic acid ((R)-2-oxo-2,...)
Affinity DataIC50: 83nMAssay Description:Inhibitory concentration against recombinant human muscle glycogen phosphorylase a (HMGPa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycogen phosphorylase, liver form(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136430BDBM50136430(5-Chloro-1H-indole-2-carboxylic acid ((R)-2-oxo-2,...)
Affinity DataIC50: 99nMAssay Description:Inhibitory concentration against recombinant human liver glycogen phosphorylase a (HLGPa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycogen phosphorylase, liver form(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136430BDBM50136430(5-Chloro-1H-indole-2-carboxylic acid ((R)-2-oxo-2,...)
Affinity DataIC50: 99nMAssay Description:Inhibition of human liver glycogen phosphorylase 1a assessed as release of phosphate from glucose-1- phosphate after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed