BDBM50136599 3-[(3R,4R)-3,4-Dimethyl-1-(4-methylsulfanyl-benzyl)-piperidin-4-yl]-benzamide::CHEMBL336664

SMILES CSc1ccc(CN2CC[C@](C)([C@@H](C)C2)c2cccc(c2)C(N)=O)cc1

InChI Key InChIKey=CRANKTQZFCMJPC-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50136599   

TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50136599(3-[(3R,4R)-3,4-Dimethyl-1-(4-methylsulfanyl-benzyl...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of binding of the non-selective opioid antagonist, [3H]diprenorphine, to cloned human mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50136599(3-[(3R,4R)-3,4-Dimethyl-1-(4-methylsulfanyl-benzyl...)
Affinity DataKi:  110nMAssay Description:Inhibition of [3H]diprenorphine binding to the cloned human delta opioid receptors using 10 uM concentration of the compoundMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50136599(3-[(3R,4R)-3,4-Dimethyl-1-(4-methylsulfanyl-benzyl...)
Affinity DataKi:  120nMAssay Description:Binding affinity at cloned human kappa opioid receptor by [3H]diprenorphine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed