BDBM50136950 CHEMBL446171::N-{4-[4-((S)-6-Hydroxy-2,5,7,8-tetramethyl-chroman-2-carbonyl)-cyclohexyl]-phenyl}-thiophene-2-carboxamidine

SMILES Cc1c(C)c2O[C@@](C)(CCc2c(C)c1O)C(=O)C1CCC(CC1)c1ccc(cc1)N=C(N)c1cccs1

InChI Key InChIKey=FALMIVYOZSZXLI-SGSZRKLKSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50136950   

TargetNitric oxide synthase, brain(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50136950(CHEMBL446171 | N-{4-[4-((S)-6-Hydroxy-2,5,7,8-tetr...)
Affinity DataKi:  920nMAssay Description:Inhibitory activity against neuronal nitric oxide synthaseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50136950(CHEMBL446171 | N-{4-[4-((S)-6-Hydroxy-2,5,7,8-tetr...)
Affinity DataKi:  1.10E+5nMAssay Description:Inhibitory activity against endothelial nitric oxide synthase (eNOS)Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50136950(CHEMBL446171 | N-{4-[4-((S)-6-Hydroxy-2,5,7,8-tetr...)
Affinity DataKi: >3.00E+5nMAssay Description:Inhibitory activity against Inducible nitric oxide synthaseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed