BDBM50137582 CHEMBL292930::[4-(3-{2-[5-Methylsulfamoyl-2-oxo-1,2-dihydro-indol-(3Z)-ylidenemethyl]-4,5,6,7-tetrahydro-1H-indol-3-yl}-propyl)-piperazin-1-yl]-acetic acid

SMILES CNS(=O)(=O)c1ccc2c(c1)/C(=C/c1[nH]c3c(c1CCCN1CCN(CC(=O)O)CC1)CCCC3)C(=O)N2

InChI Key InChIKey=BPMIILWVKNVIKR-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50137582   

TargetTyrosine-protein kinase Yes(Human)
Sugen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50137582BDBM50137582([4-(3-{2-[5-Methylsulfamoyl-2-oxo-1,2-dihydro-indo...)
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against Yes tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50137582BDBM50137582([4-(3-{2-[5-Methylsulfamoyl-2-oxo-1,2-dihydro-indo...)
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against cellular Src protein tyrosine kinase using the actin ring assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Sugen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50137582BDBM50137582([4-(3-{2-[5-Methylsulfamoyl-2-oxo-1,2-dihydro-indo...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against Lck tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Sugen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50137582BDBM50137582([4-(3-{2-[5-Methylsulfamoyl-2-oxo-1,2-dihydro-indo...)
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against Fibroblast growth factor receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fyn(Human)
Sugen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50137582BDBM50137582([4-(3-{2-[5-Methylsulfamoyl-2-oxo-1,2-dihydro-indo...)
Affinity DataIC50: 400nMAssay Description:Inhibitory activity against Fyn tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50137582BDBM50137582([4-(3-{2-[5-Methylsulfamoyl-2-oxo-1,2-dihydro-indo...)
Affinity DataIC50: 400nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50137582BDBM50137582([4-(3-{2-[5-Methylsulfamoyl-2-oxo-1,2-dihydro-indo...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibitory activity against PDGFRbeta tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50137582BDBM50137582([4-(3-{2-[5-Methylsulfamoyl-2-oxo-1,2-dihydro-indo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against cellular Src protein tyrosine kinase using the actin ring assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed