BDBM50137830 6-(5-Hydroxy-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-hexanoic acid (2-amino-phenyl)-amide::CHEMBL314301

SMILES Nc1ccccc1NC(=O)CCCCCN1C(=O)c2ccc(O)cc2C1=O

InChI Key InChIKey=WMHFSCVKPHKILO-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50137830   

TargetHistone deacetylase(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137830(6-(5-Hydroxy-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-...)
Affinity DataEC50:  1.00E+4nMAssay Description:Effect on induced hyperacetylation of histones in whole cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137830(6-(5-Hydroxy-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-...)
Affinity DataIC50:  3.00E+3nMAssay Description:Ability to inhibit recombinant human histone deacetylase 1 (HDAC-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed