BDBM50137844 6-(1-Oxo-1,3-dihydro-isoindol-2-yl)-hexanoic acid (2-amino-phenyl)-amide::CHEMBL318821

SMILES Nc1ccccc1NC(=O)CCCCCN1Cc2ccccc2C1=O

InChI Key InChIKey=GYVLADWHXWFTMQ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50137844   

TargetHistone deacetylase(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137844(6-(1-Oxo-1,3-dihydro-isoindol-2-yl)-hexanoic acid ...)
Affinity DataEC50:  9.90E+4nMAssay Description:Effect on induced hyperacetylation of histones in whole cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137844(6-(1-Oxo-1,3-dihydro-isoindol-2-yl)-hexanoic acid ...)
Affinity DataIC50:  4.00E+3nMAssay Description:Ability to inhibit recombinant human histone deacetylase 1 (HDAC-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed