BDBM50137848 6-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-hexanoic acid (2-amino-phenyl)-amide::CHEMBL317339

SMILES Nc1ccccc1NC(=O)CCCCCN1C(=O)c2ccccc2C1=O

InChI Key InChIKey=TWOHAJFOZUGOAL-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50137848   

TargetHistone deacetylase(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137848(6-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-hexanoic a...)
Affinity DataEC50:  5.00E+3nMAssay Description:Effect on induced hyperacetylation of histones in whole cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137848(6-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-hexanoic a...)
Affinity DataIC50:  2.00E+3nMAssay Description:Ability to inhibit recombinant human histone deacetylase 1 (HDAC-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed