BDBM50138317 (S)-3-({8-[(1H-Benzoimidazol-2-ylamino)-methyl]-1-oxa-2-aza-spiro[4.5]dec-2-ene-3-carbonyl}-amino)-2-(2,4,6-trimethyl-benzenesulfonyl)-propionic acid::CHEMBL419795

SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)[C@@H](CNC(=O)C1=NOC2(C1)CCC(CNc1nc3ccccc3[nH]1)CC2)C(O)=O

InChI Key InChIKey=BSJOIRBVGVDOJC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50138317   

TargetIntegrin alpha-5/beta-1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50138317((S)-3-({8-[(1H-Benzoimidazol-2-ylamino)-methyl]-1-...)
Affinity DataIC50: 170nMAssay Description:Alpha-5 beta-1 antagonism using an ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50138317((S)-3-({8-[(1H-Benzoimidazol-2-ylamino)-methyl]-1-...)
Affinity DataIC50: 440nMAssay Description:Evaluated in an functional alpha-v beta-3 antagonism assay, involving adhesion of beta-3-transfected 293 cells to fibrinogen (alpha-v beta-3 293 beta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed