BDBM50138384 CHEMBL133823::N-(4-{4-[4-(Piperazine-1-sulfonyl)-phenyl]-pyrimidin-2-ylamino}-phenyl)-methanesulfonamide

SMILES CS(=O)(=O)Nc1ccc(Nc2nccc(n2)-c2ccc(cc2)S(=O)(=O)N2CCNCC2)cc1

InChI Key InChIKey=MAFLHOXURZCIKH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50138384   

LigandPNGBDBM50138384(CHEMBL133823 | N-(4-{4-[4-(Piperazine-1-sulfonyl)-...)
Affinity DataIC50:  331nMAssay Description:Inhibitory activity against IKK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50138384(CHEMBL133823 | N-(4-{4-[4-(Piperazine-1-sulfonyl)-...)
Affinity DataIC50:  43nMAssay Description:Inhibition of human IKKbeta using GST-IkappaBalpha as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50138384(CHEMBL133823 | N-(4-{4-[4-(Piperazine-1-sulfonyl)-...)
Affinity DataIC50:  43nMAssay Description:Inhibitory activity against IKK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed