BDBM50138385 (4-Methanesulfinyl-phenyl)-{4-[4-(piperazine-1-sulfonyl)-phenyl]-pyrimidin-2-yl}-amine::CHEMBL134010

SMILES CS(=O)c1ccc(Nc2nccc(n2)-c2ccc(cc2)S(=O)(=O)N2CCNCC2)cc1

InChI Key InChIKey=LOVZMSWXBKTPFD-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50138385   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Celltech R&D

Curated by ChEMBL

LigandBDBM50138385((4-Methanesulfinyl-phenyl)-{4-[4-(piperazine-1-sul...)Copy SMILESCopy InChI

Affinity DataIC50:  91nMAssay Description:Inhibitory activity against IKK2More data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Celltech R&D

Curated by ChEMBL

LigandBDBM50138385((4-Methanesulfinyl-phenyl)-{4-[4-(piperazine-1-sul...)Copy SMILESCopy InChI

Affinity DataIC50:  2.34E+3nMAssay Description:Inhibitory activity against IKK1More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL