BDBM50139054 CHEMBL2023335

SMILES CCCS(=O)(=O)Nc1ccc(F)c(c1F)-c1ccc2cc(N)ncc2c1

InChI Key InChIKey=ARJQWXGFNXYBIQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50139054   

TargetSerine/threonine-protein kinase B-raf(Human)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50139054(CHEMBL2023335)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of B-Raf V600E mutant (unknown origin) by lantha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50139054(CHEMBL2023335)
Affinity DataIC50: 549nMAssay Description:Inhibition of full-length B-Raf V600E mutant assessed as reduction in incorporation of radiolabeled phosphate from [gamma-33P]ATP into FSBA-modified ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed