BDBM50139354 1-[6-(2-Dimethylamino-ethylsulfanyl)-pyridin-2-yl]-cyclohexanol::CHEMBL159143

SMILES CN(C)CCSc1cccc(n1)C1(O)CCCCC1

InChI Key InChIKey=NJQKIZFGISMHHC-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50139354   

Target5-hydroxytryptamine receptor 7(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139354(1-[6-(2-Dimethylamino-ethylsulfanyl)-pyridin-2-yl]...)
Affinity DataKi:  7.20nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 7 receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in CHO ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139354(1-[6-(2-Dimethylamino-ethylsulfanyl)-pyridin-2-yl]...)
Affinity DataKi:  41nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 1A receptor by the displacement of [3H]5-HT radioligand from the cloned receptor expressed in HeLa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139354(1-[6-(2-Dimethylamino-ethylsulfanyl)-pyridin-2-yl]...)
Affinity DataKi:  480nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 2A receptor by the displacement of [3H]ketanserin radioligand from the cloned receptor expressed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139354(1-[6-(2-Dimethylamino-ethylsulfanyl)-pyridin-2-yl]...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity towards human dopamine receptor D2 by the displacement of [3H]spiperone radioligand from the cloned receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed