BDBM50139423 CHEMBL2011285

SMILES O=C(N1CCN(Cc2ccccc2)CC1)c1cc(=O)c2c(OCc3ccccc3)cccc2o1

InChI Key InChIKey=RKFOXQNWRPAKDL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50139423   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50139423(CHEMBL2011285)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of human ABCG2 expressed in HEK293 cells by mitoxantrone flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2017
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50139423(CHEMBL2011285)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of ABCB1 in human KBV1 cells assessed as inhibition of calcein-AM effluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2017
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50139423(CHEMBL2011285)
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of ABCG2 in human MCF7/Topo cells by Hoechst 33342 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2017
Entry Details Article
PubMed
TargetMultidrug resistance-associated protein 1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50139423(CHEMBL2011285)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human MRP1 transfected in MDCK2 cells assessed as inhibition of calcein-AM effluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2017
Entry Details Article
PubMed