BDBM50139572 4-{5-[(2-Cyclohexylmethyl-3-oxo-2,3,4,5-tetrahydro-1H-benzo[c]azepin-4-ylamino)-methyl]-imidazol-1-ylmethyl}-benzonitrile::CHEMBL348850

SMILES O=C1C(Cc2ccccc2CN1CC1CCCCC1)NCc1cncn1Cc1ccc(cc1)C#N

InChI Key InChIKey=GERFWDRHAJVQRY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50139572   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50139572(4-{5-[(2-Cyclohexylmethyl-3-oxo-2,3,4,5-tetrahydro...)
Affinity DataIC50:  47nMAssay Description:Inhibition of farnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed