BDBM50139606 CHEMBL168049::N-(2-Dimethylamino-ethyl)-5-{4-[3-(2-methoxy-5-trifluoromethyl-phenyl)-ureido]-phenoxy}-nicotinamide

SMILES COc1ccc(cc1NC(=O)Nc1ccc(Oc2cncc(c2)C(=O)NCCN(C)C)cc1)C(F)(F)F

InChI Key InChIKey=SEGSQKVNLZOYPP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50139606   

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139606(N-(2-Dimethylamino-ethyl)-5-{4-[3-(2-methoxy-5-tri...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed