BDBM50139899 CHEMBL11285::N-{(S)-1-[(3R,4R)-4-(3-Hydroxy-phenyl)-3,4-dimethyl-piperidin-1-ylmethyl]-2-methyl-propyl}-3-phenyl-propionamide

SMILES CC(C)[C@@H](CN1CC[C@](C)([C@@H](C)C1)c1cccc(O)c1)NC(=O)CCc1ccccc1

InChI Key InChIKey=GOMFYDFQXWRAGC-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50139899   

TargetKappa-type opioid receptor(Guinea pig)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50139899(N-{(S)-1-[(3R,4R)-4-(3-Hydroxy-phenyl)-3,4-dimethy...)
Affinity DataKi:  446nMAssay Description:Binding affinity of compound for Opioid receptor kappa 1 was determined using [3H]U-69593 as radioligand from guinea pig caudateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50139899(N-{(S)-1-[(3R,4R)-4-(3-Hydroxy-phenyl)-3,4-dimethy...)
Affinity DataKi:  946nMAssay Description:Binding affinity of compound for Opioid receptor mu 1 was determined using [3H]DAMGO as radioligand from rat brain tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50139899(N-{(S)-1-[(3R,4R)-4-(3-Hydroxy-phenyl)-3,4-dimethy...)
Affinity DataKi: >5.05E+3nMAssay Description:Binding affinity of compound for opioid receptor delta 1 was determined using [3H]DADLE as radioligand from rat brain tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed