BDBM50141088 6-[4-(2-Dimethylamino-ethoxy)-6,7,8,9-tetrahydro-5H-benzocyclohepten-1-yl]-pyridin-2-ylamine::CHEMBL42969

SMILES CN(C)CCOc1ccc(-c2cccc(N)n2)c2CCCCCc12

InChI Key InChIKey=UWOZQXPAWBDKCL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50141088   

TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141088(6-[4-(2-Dimethylamino-ethoxy)-6,7,8,9-tetrahydro-5...)
Affinity DataIC50:  93nMAssay Description:In vitro inhibition of rat neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141088(6-[4-(2-Dimethylamino-ethoxy)-6,7,8,9-tetrahydro-5...)
Affinity DataIC50:  5.75E+3nMAssay Description:In vitro inhibition of human endothelial nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141088(6-[4-(2-Dimethylamino-ethoxy)-6,7,8,9-tetrahydro-5...)
Affinity DataIC50:  2.10E+3nMAssay Description:In vitro inhibition of human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141088(6-[4-(2-Dimethylamino-ethoxy)-6,7,8,9-tetrahydro-5...)
Affinity DataIC50:  109nMAssay Description:In vitro inhibition of human neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed