BDBM50141151 But-2-ynoic acid [5-(3-bromo-phenylamino)-6-cyano-[1,8]naphthyridin-3-yl]-amide::CHEMBL31745

SMILES CC#CC(=O)Nc1cnc2ncc(C#N)c(Nc3cccc(Br)c3)c2c1

InChI Key InChIKey=HPIMRCZSRFWHDE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50141151   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50141151(But-2-ynoic acid [5-(3-bromo-phenylamino)-6-cyano-...)
Affinity DataIC50:  6.27E+3nMAssay Description:Inhibition of peptide substrate phosphorylation by epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50141151(But-2-ynoic acid [5-(3-bromo-phenylamino)-6-cyano-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of epidermal growth factor receptor kinase autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed