BDBM50141322 3-{4-[3-(1,4,5,6-Tetrahydro-pyrimidin-2-ylamino)-benzoylamino]-phenyl}-acrylic acid::CHEMBL417330

SMILES OC(=O)C=Cc1ccc(NC(=O)c2cccc(NC3=NCCCN3)c2)cc1

InChI Key InChIKey=ZPRQEMGTRXGZPE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50141322   

TargetIntegrin alpha-V/beta-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141322(3-{4-[3-(1,4,5,6-Tetrahydro-pyrimidin-2-ylamino)-b...)
Affinity DataIC50:  219nMAssay Description:Binding affinity towards alpha V-beta1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-IIb/beta-3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141322(3-{4-[3-(1,4,5,6-Tetrahydro-pyrimidin-2-ylamino)-b...)
Affinity DataIC50:  528nMAssay Description:Binding affinity towards alpha V-beta3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-V/beta-3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141322(3-{4-[3-(1,4,5,6-Tetrahydro-pyrimidin-2-ylamino)-b...)
Affinity DataIC50:  2nMAssay Description:Binding affinity towards alpha V/beta3 receptor by solid-phase receptor binding assays (SPRA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-V/beta-5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141322(3-{4-[3-(1,4,5,6-Tetrahydro-pyrimidin-2-ylamino)-b...)
Affinity DataIC50:  7.60nMAssay Description:Binding affinity towards alpha IIb/beta3 integrin by solid-phase receptor binding assay (SPRA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-V/beta-3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141322(3-{4-[3-(1,4,5,6-Tetrahydro-pyrimidin-2-ylamino)-b...)
Affinity DataIC50:  1.80nMAssay Description:Binding affinity towards alpha V-beta5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed