BDBM50142177 2-{4-[(Acetimidoyl-methyl-amino)-methyl]-benzoylamino}-5-chloro-N-(5-chloro-pyridin-2-yl)-benzamide::CHEMBL176243

SMILES CN(Cc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1)C(C)=N

InChI Key InChIKey=XKNLDUVCXUEIJO-UHFFFAOYSA-N

Data  2 KI  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50142177   

TargetCoagulation factor X(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142177(2-{4-[(Acetimidoyl-methyl-amino)-methyl]-benzoylam...)
Affinity DataKi:  0.600nMAssay Description:In vitro inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142177(2-{4-[(Acetimidoyl-methyl-amino)-methyl]-benzoylam...)
Affinity DataKi:  0.600nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine protease 1(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142177(2-{4-[(Acetimidoyl-methyl-amino)-methyl]-benzoylam...)
Affinity DataIC50: >1.10E+4nMAssay Description:Inhibitory activity against trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTissue-type plasminogen activator(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142177(2-{4-[(Acetimidoyl-methyl-amino)-methyl]-benzoylam...)
Affinity DataIC50: >1.10E+4nMAssay Description:Inhibitory activity against tissue type plasminogen activator.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142177(2-{4-[(Acetimidoyl-methyl-amino)-methyl]-benzoylam...)
Affinity DataIC50:  0.900nMAssay Description:In vitro inhibitory activity against coagulation factor X.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142177(2-{4-[(Acetimidoyl-methyl-amino)-methyl]-benzoylam...)
Affinity DataIC50: >1.10E+4nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlasma kallikrein(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142177(2-{4-[(Acetimidoyl-methyl-amino)-methyl]-benzoylam...)
Affinity DataIC50:  500nMAssay Description:Inhibitory activity against kallikreinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlasminogen(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142177(2-{4-[(Acetimidoyl-methyl-amino)-methyl]-benzoylam...)
Affinity DataIC50: >1.10E+4nMAssay Description:Inhibitory activity against plasmin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVitamin K-dependent protein C(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142177(2-{4-[(Acetimidoyl-methyl-amino)-methyl]-benzoylam...)
Affinity DataIC50: >1.10E+4nMAssay Description:Inhibitory activity against activated protein CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed