BDBM50142321 2-[4-(Difluoro-phosphono-methyl)-benzyl]-2-(4-methanesulfonyl-benzyl)-malonic acid dibenzyl ester::CHEMBL267981

SMILES CS(=O)(=O)c1ccc(CC(Cc2ccc(cc2)C(F)(F)P(O)(O)=O)(C(=O)OCc2ccccc2)C(=O)OCc2ccccc2)cc1

InChI Key InChIKey=XTVJCIYMMNRSNG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50142321   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50142321(2-[4-(Difluoro-phosphono-methyl)-benzyl]-2-(4-meth...)
Affinity DataIC50:  7.20E+3nMAssay Description:In vitro inhibitory activity against protein tyrosine phosphatase 1B (PTP1B) was determined in fluorescein diphosphate (FDP) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetReceptor-type tyrosine-protein phosphatase C(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50142321(2-[4-(Difluoro-phosphono-methyl)-benzyl]-2-(4-meth...)
Affinity DataIC50: >5.00E+4nMAssay Description:In vitro inhibitory activity against CD45 protein-tyrosine phosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50142321(2-[4-(Difluoro-phosphono-methyl)-benzyl]-2-(4-meth...)
Affinity DataIC50:  940nMAssay Description:In vitro inhibitory activity against protein tyrosine phosphatase 1B (PTP1B) was determined in fluorescein diphosphate (FDP) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed