BDBM50142440 CHEMBL3759727

SMILES COc1cccc(CNC(=O)c2cc(cc(C)n2)-c2nnn(C[C@H]3CC[C@H](CC3)NC(C)=O)n2)c1

InChI Key InChIKey=FVKRTYIXQYFBNM-RVWIWJKTSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50142440   

TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50142440(CHEMBL3759727)
Affinity DataKi:  1.40nMAssay Description:Inhibition of full length human recombinant MMP13 using MCA-Arg-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-Glu-Arg-NH2 as substrate preincubated for 60 mins followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50142440(CHEMBL3759727)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of MMP3 (unknown origin) catalytic domain using Mca-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 as substrate preincubated for 60 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed