BDBM50142524 Acetic acid 4-[2-(4-acetoxy-benzoylamino)-phenylcarbamoyl]-phenyl ester::CHEMBL45239

SMILES CC(=O)Oc1ccc(cc1)C(=O)Nc1ccccc1NC(=O)c1ccc(OC(C)=O)cc1

InChI Key InChIKey=AIIXVAGTSFTWIF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50142524   

TargetDNA topoisomerase 1(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50142524(Acetic acid 4-[2-(4-acetoxy-benzoylamino)-phenylca...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed formMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed