BDBM50142528 CHEMBL296351::N-Benzothiazol-2-yl-3,4,5-trihydroxy-benzamide

SMILES Oc1cc(cc(O)c1O)C(=O)Nc1nc2ccccc2s1

InChI Key InChIKey=WHTLHKPXPPUCSN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50142528   

TargetDNA topoisomerase 1(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50142528(CHEMBL296351 | N-Benzothiazol-2-yl-3,4,5-trihydrox...)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed formMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed