BDBM50142708 CHEMBL3760011

SMILES CCOC(=O)c1c(CSc2ccccc2Cl)n(CC)c2c1cc(OCC)c1ccccc21

InChI Key InChIKey=BPJYTFWLISDGDU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50142708   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Second University of Naples

Curated by ChEMBL
LigandPNGBDBM50142708(CHEMBL3760011)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 using arachidonic acid as substrate assessed as LTB4 formation preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Second University of Naples

Curated by ChEMBL
LigandPNGBDBM50142708(CHEMBL3760011)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 5-LOX in human intact polymorphonuclear leukocytes preincubated for 15 mins with CaCl2, A23187 measured after 10 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed