BDBM50142751 CHEMBL3759086

SMILES CCOC(=O)c1c(CSc2ccccc2Cl)[nH]c2c1cc(O)c1ccccc21

InChI Key InChIKey=DSFGUFSQHQCQIQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50142751   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Second University of Naples

Curated by ChEMBL
LigandPNGBDBM50142751(CHEMBL3759086)
Affinity DataIC50:  820nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 using arachidonic acid as substrate assessed as LTB4 formation preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Second University of Naples

Curated by ChEMBL
LigandPNGBDBM50142751(CHEMBL3759086)
Affinity DataIC50:  182nMAssay Description:Inhibition of 5-LOX in human intact polymorphonuclear leukocytes preincubated for 15 mins with CaCl2, A23187 measured after 10 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed