BDBM50143182 CHEMBL3759167

SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@@H]1CCCCNC(=O)C[C@H](NC(=O)[C@@H](Cc2cccc3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC1=O)C(N)=O

InChI Key InChIKey=KZPMZJUWJIEYBH-UHFFFAOYSA-N

Data  6 KI  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50143182   

TargetMu-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50143182(CHEMBL3759167)
Affinity DataKi:  0.25nMAssay Description:Displacement of [3H]DAMGO from Wistar rat brain membrane MOPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50143182(CHEMBL3759167)
Affinity DataKi:  0.25nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain homogenates by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50143182(CHEMBL3759167)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]nor-BNI from KOR in Dunkin Hartley guinea pig brain homogenates by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50143182(CHEMBL3759167)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]-norBNI from Wistar rat brain membrane KOPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50143182(CHEMBL3759167)
Affinity DataEC50:  5.60nMAssay Description:Agonist activity at human recombinant MOR expressed in CHO cells assessed as calcium mobilization by Fluo-4 AM based fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50143182(CHEMBL3759167)
Affinity DataEC50:  5.60nMAssay Description:Agonist activity at human recombinant MOP expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50143182(CHEMBL3759167)
Affinity DataEC50:  42nMAssay Description:Agonist activity at human recombinant KOR expressed in CHO cells assessed as calcium mobilization by Fluo-4 AM based fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50143182(CHEMBL3759167)
Affinity DataKi:  51nMAssay Description:Displacement of [3H]-[Ile5,6]-deltorphin-2 from Wistar rat brain membrane DOPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDelta-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50143182(CHEMBL3759167)
Affinity DataKi:  51nMAssay Description:Displacement of [3H][Ile5,6]deltorphin-2 from DOR in Wistar rat brain homogenates by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50143182(CHEMBL3759167)
Affinity DataEC50:  65nMAssay Description:Agonist activity at human recombinant DOR expressed in CHO cells assessed as calcium mobilization by Fluo-4 AM based fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed