BDBM50143774 3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid [2-(2-methanesulfonyl-acetyl)-4,6-dimethyl-phenyl]-amide::CHEMBL305602

SMILES Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2c(C)cc(C)cc2C(=O)CS(C)(=O)=O)c1Cl

InChI Key InChIKey=VEKIKAXYTJSNHF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50143774   

TargetEndothelin-1 receptor(Rat)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143774(3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiop...)
Affinity DataIC50: 0.100nMAssay Description:Displacement of [125I]ET-1 from Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed