BDBM50144214 CHEMBL3759322

SMILES SCCCCCCNC(=O)c1cc(n[nH]1)-c1c[nH]c2ccccc12

InChI Key InChIKey=QTJRTUWSBZMZMT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50144214   

TargetHistone deacetylase 6(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50144214(CHEMBL3759322)
Affinity DataIC50: 33nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-Lys(Ac)-AMC as substrate preincubated for 15 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50144214(CHEMBL3759322)
Affinity DataIC50: 70nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys(Ac)-AMC as substrate preincubated for 15 mins followed by substrate addition meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50144214(CHEMBL3759322)
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant human HDAC1 using Boc-Lys(Ac)-AMC as substrate preincubated for 15 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed