BDBM50144216 CHEMBL3760013

SMILES SCCCCCCNC(=O)c1cc(n[nH]1)-c1cnccn1

InChI Key InChIKey=GYWQCXUVPDWXRB-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50144216   

TargetHistone deacetylase 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50144216(CHEMBL3760013)
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human HDAC1 using Boc-Lys(Ac)-AMC as substrate preincubated for 15 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50144216(CHEMBL3760013)
Affinity DataIC50: 18nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys(Ac)-AMC as substrate preincubated for 15 mins followed by substrate addition meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50144216(CHEMBL3760013)
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-Lys(Ac)-AMC as substrate preincubated for 15 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50144216(CHEMBL3760013)
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human HDAC3 using Boc-Lys(Ac)-AMC as substrate preincubated for 15 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50144216(CHEMBL3760013)
Affinity DataIC50: 68nMAssay Description:Inhibition of recombinant human HDAC2 using Boc-Lys(Ac)-AMC as substrate preincubated for 15 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50144216(CHEMBL3760013)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human HDAC4 using Boc-Lys(TFA)-AMC as substrate preincubated for 15 mins followed by substrate addition measured after 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50144216(CHEMBL3760013)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human HDAC11 using Boc-Lys(TFA)-AMC as substrate preincubated for 15 mins followed by substrate addition measured after 60 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50144216(CHEMBL3760013)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human HDAC8 using Boc-Lys(TFA)-AMC as substrate preincubated for 15 mins followed by substrate addition measured after 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed