BDBM50144225 CHEMBL3759606

SMILES COc1ccc2ccc3occ(CCNC(=O)C4CC4)c3c2c1

InChI Key InChIKey=MEMHWYDEBRSNOK-UHFFFAOYSA-N

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50144225   

TargetMelatonin receptor type 1B(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50144225(CHEMBL3759606)
Affinity DataEC50:  3.20nMAssay Description:Intrinsic activity at human MT2 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50144225(CHEMBL3759606)
Affinity DataEC50:  5.20nMAssay Description:Intrinsic activity at human MT1 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50144225(CHEMBL3759606)
Affinity DataKi:  13nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in CHO cell membranes after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50144225(CHEMBL3759606)
Affinity DataKi:  24nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in CHO cell membranes after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50144225(CHEMBL3759606)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to 5-HT2C receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed