BDBM50144244 CHEMBL63571::N,N-Diethyl-4-[phenyl-(8-propyl-8-aza-bicyclo[3.2.1]oct-3-ylidene)-methyl]-benzamide

SMILES CCCN1C2CCC1CC(=C(c1ccccc1)c1ccc(C(=O)N(CC)CC)cc1)C2

InChI Key InChIKey=ISSXPQNDRCLGFP-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50144244   

TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144244BDBM50144244(N,N-Diethyl-4-[phenyl-(8-propyl-8-aza-bicyclo[3.2....)
Affinity DataKi:  0.390nMAssay Description:Binding affinity for delta opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144244BDBM50144244(N,N-Diethyl-4-[phenyl-(8-propyl-8-aza-bicyclo[3.2....)
Affinity DataEC50:  43nMAssay Description:Effective concentration against stimulation of [35S]GTP-gamma-S, binding in CHO cells transfected with the human opioid receptor delta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144244BDBM50144244(N,N-Diethyl-4-[phenyl-(8-propyl-8-aza-bicyclo[3.2....)
Affinity DataKi:  289nMAssay Description:Binding affinity for mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed