BDBM50144253 CHEMBL63400::N,N-Diethyl-4-({8-[2-(4-fluoro-phenyl)-ethyl]-8-aza-bicyclo[3.2.1]oct-3-ylidene}-phenyl-methyl)-benzamide

SMILES CCN(CC)C(=O)c1ccc(C(=C2CC3CCC(C2)N3CCc2ccc(F)cc2)c2ccccc2)cc1

InChI Key InChIKey=UFCSZAIRFHNKLA-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50144253   

TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144253BDBM50144253(N,N-Diethyl-4-({8-[2-(4-fluoro-phenyl)-ethyl]-8-az...)
Affinity DataKi:  2.60nMAssay Description:Binding affinity for delta opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144253BDBM50144253(N,N-Diethyl-4-({8-[2-(4-fluoro-phenyl)-ethyl]-8-az...)
Affinity DataEC50:  27nMAssay Description:Effective concentration against stimulation of [35S]GTP-gamma-S, binding in CHO cells transfected with the human opioid receptor delta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144253BDBM50144253(N,N-Diethyl-4-({8-[2-(4-fluoro-phenyl)-ethyl]-8-az...)
Affinity DataKi:  393nMAssay Description:Binding affinity for mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed