BDBM50144260 4-[(8-Phenethyl-8-aza-bicyclo[3.2.1]oct-3-ylidene)-phenyl-methyl]-N,N-dipropyl-benzamide::CHEMBL292794

SMILES CCCN(CCC)C(=O)c1ccc(C(=C2CC3CCC(C2)N3CCc2ccccc2)c2ccccc2)cc1

InChI Key InChIKey=VNDBQFQNJQVPAG-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50144260   

TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144260BDBM50144260(4-[(8-Phenethyl-8-aza-bicyclo[3.2.1]oct-3-ylidene)...)
Affinity DataKi:  7.40nMAssay Description:Binding affinity for delta opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144260BDBM50144260(4-[(8-Phenethyl-8-aza-bicyclo[3.2.1]oct-3-ylidene)...)
Affinity DataKi:  644nMAssay Description:Binding affinity for mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144260BDBM50144260(4-[(8-Phenethyl-8-aza-bicyclo[3.2.1]oct-3-ylidene)...)
Affinity DataEC50:  3.56E+3nMAssay Description:Effective concentration against stimulation of [35S]GTP-gamma-S, binding in CHO cells transfected with the human opioid receptor delta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed