BDBM50144580 (R)-1-(4-{4-[3-(4-Chloro-phenyl)-[1,2,4]oxadiazol-5-yl]-butyryl}-piperazine-1-carbonyl)-4-oxo-3-piperidin-4-ylmethyl-azetidine-2-carboxylic acid::CHEMBL70766

SMILES OC(=O)[C@@H]1[C@@H](CC2CCNCC2)C(=O)N1C(=O)N1CCN(CC1)C(=O)CCCc1nc(no1)-c1ccc(Cl)cc1

InChI Key InChIKey=RTVGVVNPBUBPDD-OFNKIYASSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50144580   

TargetTryptase beta-2/delta/gamma(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144580((R)-1-(4-{4-[3-(4-Chloro-phenyl)-[1,2,4]oxadiazol-...)
Affinity DataIC50:  5nMAssay Description:Inhibitory activity against human tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144580((R)-1-(4-{4-[3-(4-Chloro-phenyl)-[1,2,4]oxadiazol-...)
Affinity DataIC50:  150nMAssay Description:Inhibitory activity against bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed