BDBM50144851 (2R,3S)-3-(4-Hydroxy-phenyl)-2-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-2,3-dihydro-benzo[1,4]oxathiin-6-ol::CHEMBL539927

SMILES Oc1ccc(cc1)[C@@H]1Sc2cc(O)ccc2O[C@@H]1c1ccc(OCCN2CCCCC2)cc1

InChI Key InChIKey=TWZNCTCQAGRUGQ-SXOMAYOGSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50144851   

TargetEstrogen receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144851((2R,3S)-3-(4-Hydroxy-phenyl)-2-[4-(2-piperidin-1-y...)
Affinity DataIC50:  9.60nMAssay Description:Potency in cellular transactivation assay utilizing HEK-293 cells stably co-transfected with human estrogen receptor alpha and the alkaline phosphata...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144851((2R,3S)-3-(4-Hydroxy-phenyl)-2-[4-(2-piperidin-1-y...)
Affinity DataIC50:  143nMAssay Description:Displacement of [3H]-17-beta-estradiol from full length human estrogen receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144851((2R,3S)-3-(4-Hydroxy-phenyl)-2-[4-(2-piperidin-1-y...)
Affinity DataIC50:  3nMAssay Description:Binding affinity towards human recombinant Estrogen receptor alpha was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144851((2R,3S)-3-(4-Hydroxy-phenyl)-2-[4-(2-piperidin-1-y...)
Affinity DataIC50:  188nMAssay Description:In vitro binding affinity for Estrogen receptor alpha in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144851((2R,3S)-3-(4-Hydroxy-phenyl)-2-[4-(2-piperidin-1-y...)
Affinity DataIC50:  1.40E+3nMAssay Description:In vitro binding affinity for Estrogen receptor beta in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144851((2R,3S)-3-(4-Hydroxy-phenyl)-2-[4-(2-piperidin-1-y...)
Affinity DataIC50:  3nMAssay Description:Displacement of [3H]-17-beta-estradiol from full length human estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144851((2R,3S)-3-(4-Hydroxy-phenyl)-2-[4-(2-piperidin-1-y...)
Affinity DataIC50:  3nMAssay Description:Binding affinity towards human recombinant Estrogen receptor alpha was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144851((2R,3S)-3-(4-Hydroxy-phenyl)-2-[4-(2-piperidin-1-y...)
Affinity DataIC50:  143nMAssay Description:Binding affinity towards human recombinant Estrogen receptor beta was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144851((2R,3S)-3-(4-Hydroxy-phenyl)-2-[4-(2-piperidin-1-y...)
Affinity DataIC50:  52nMAssay Description:Displacement of [3H]-17-beta-estradiol from full length human estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144851((2R,3S)-3-(4-Hydroxy-phenyl)-2-[4-(2-piperidin-1-y...)
Affinity DataIC50:  143nMAssay Description:Displacement of [3H]-17-beta-estradiol from full length human estrogen receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144851((2R,3S)-3-(4-Hydroxy-phenyl)-2-[4-(2-piperidin-1-y...)
Affinity DataIC50:  3nMAssay Description:Displacement of [3H]-17-beta-estradiol from full length human estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144851((2R,3S)-3-(4-Hydroxy-phenyl)-2-[4-(2-piperidin-1-y...)
Affinity DataIC50:  143nMAssay Description:Binding affinity towards human recombinant Estrogen receptor beta was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed