BDBM50146211 2,2,2-Trifluoro-1-[7-hydroxy-4-(4-hydroxy-phenyl)-3,4-dihydro-1H-isoquinolin-2-yl]-ethanone::CHEMBL93266

SMILES Oc1ccc(cc1)C1CN(Cc2cc(O)ccc12)C(=O)C(F)(F)F

InChI Key InChIKey=DILFSAAJOWIUJZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50146211   

TargetEstrogen receptor beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50146211(2,2,2-Trifluoro-1-[7-hydroxy-4-(4-hydroxy-phenyl)-...)
Affinity DataIC50:  11nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor beta expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEstrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50146211(2,2,2-Trifluoro-1-[7-hydroxy-4-(4-hydroxy-phenyl)-...)
Affinity DataIC50:  123nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor alpha expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed