BDBM50146405 CHEMBL1622371

SMILES CCOC(=O)Nc1ccc2CCc3ccccc3N(C(=O)CN(CC)CC)c2c1

InChI Key InChIKey=AYQBYSPEGRYKFA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50146405   

TargetNuclear receptor subfamily 1 group I member 3(Human)
St. Jude Children's Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50146405BDBM50146405(CHEMBL1622371)
Affinity DataIC50: 162nMAssay Description:Inhibition of human 15-LOX-1 using arachidonic acid as substrate by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetNuclear receptor subfamily 1 group I member 3(Human)
St. Jude Children's Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50146405BDBM50146405(CHEMBL1622371)
Affinity DataIC50: 258nMAssay Description:Inhibition of VEGFR2 by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetNuclear receptor subfamily 1 group I member 3(Human)
St. Jude Children's Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50146405BDBM50146405(CHEMBL1622371)
Affinity DataIC50: 687nMAssay Description:Inverse agonist activity at GST tagged-human CAR-LBD assessed as reduction in fluorescein-PGC1 alpha coactivator recruitment after 1 hr by TR-FRET as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2017
Entry Details Article
PubMed