BDBM50148196 4-(4'-Fluoro-biphenyl-4-sulfonylamino)-tetrahydro-pyran-4-carboxylic acid hydroxyamide::CHEMBL113778

SMILES ONC(=O)C1(CCOCC1)NS(=O)(=O)c1ccc(cc1)-c1ccc(F)cc1

InChI Key InChIKey=FWJQSGAFJBBJTH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50148196   

TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50148196(4-(4'-Fluoro-biphenyl-4-sulfonylamino)-tetrahydro-...)
Affinity DataIC50:  4.40nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50148196(4-(4'-Fluoro-biphenyl-4-sulfonylamino)-tetrahydro-...)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity against human matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed