BDBM50148636 CHEMBL3769685::US9518026, Example 45::US9956214, Compound 1652

SMILES CCOc1ccc2cc(cnc2c1)-c1nn(C2CCC2)c(N)c1C(N)=O

InChI Key InChIKey=ATIDQUUZAPHKND-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50148636   

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50148636(CHEMBL3769685 | US9518026, Example 45 | US9956214,...)
Affinity DataIC50:  12nMAssay Description:Inhibition of Toxoplasma gondii CDPK1 assessed as ATP consumption using (Biotin-C6-PLARTLSVAGLPGKK) as substrate after 90 mins by luciferase reporter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50148636(CHEMBL3769685 | US9518026, Example 45 | US9956214,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human SRC using Ac-EIYGEFKKK as substrate after 90 mins by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalcium-dependent protein kinase 1(Cryptosporidium parvum)
University of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM50148636(CHEMBL3769685 | US9518026, Example 45 | US9956214,...)
Affinity DataIC50:  3nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetUncharacterized protein(Cryptosporidium parvum)
University of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM50148636(CHEMBL3769685 | US9518026, Example 45 | US9956214,...)
Affinity DataIC50:  5nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50148636(CHEMBL3769685 | US9518026, Example 45 | US9956214,...)
Affinity DataIC50:  12nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50148636(CHEMBL3769685 | US9518026, Example 45 | US9956214,...)
Affinity DataIC50:  12nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In DepthDetails US Patent